Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25831575 | 0.74 | — | — | |
| SCHEMBL18717726 | 0.73 | — | — | |
| SCHEMBL21582005 | 0.71 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL26605563 | 0.71 | — | — | |
| SCHEMBL25835823 | 0.67 | GAA (0.38) | ADORA2AADORA2B | |
| SCHEMBL18717725 | 0.67 | ADORA2A (0.33) | ADORA2AADORA2B | |
| SCHEMBL21236592 | 0.65 | LMNA (0.36) | — | |
| SCHEMBL19720500 | 0.63 | CRHR1 (0.35) | ADORA2AADORA2B | |
| SCHEMBL21582003 | 0.63 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL31094892 | 0.61 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746444-B1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2023-09-27 | — | — | EP | disclosed |
| WO-2019149734-A1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2019-08-08 | — | — | WO | disclosed |