Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.53 |
| ▸ | CHRNG | P07510 | 1/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.53 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | CHRND | Q07001 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20817354 | 0.84 | KDM1A (0.45) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG | |
| SCHEMBL21236191 | 0.84 | SLC6A4 (0.42) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG | |
| SCHEMBL22654456 | 0.84 | SLC6A4 (0.42) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG | |
| SCHEMBL22654437 | 0.84 | SLC6A4 (0.42) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG | |
| SCHEMBL23953861 | 0.83 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG | |
| SCHEMBL21512716 | 0.80 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4CHRNB2CHRNB4 | |
| SCHEMBL20065148 | 0.79 | SLC6A3 (0.59) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG | |
| SCHEMBL21512714 | 0.78 | OPRK1 (0.43) | — | |
| SCHEMBL29969542 | 0.78 | OPRK1 (0.43) | — | |
| SCHEMBL17364612 | 0.74 | HIF1A (0.33) | SLC6A3SLC6A2SLC6A4CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149734-A1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2019-08-08 | — | — | WO | disclosed |