Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240013 | 0.85 | TSHR (0.39) | TSHR | |
| SCHEMBL18227311 | 0.83 | TSHR (0.36) | TSHRKDM4EPKM | |
| SCHEMBL18250963 | 0.81 | CTSK (0.35) | TSHR | |
| SCHEMBL18240012 | 0.80 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL19153446 | 0.79 | KDM4E (0.35) | TSHRKDM4EPKM | |
| SCHEMBL20130254 | 0.75 | L3MBTL1 (0.32) | TSHR | |
| SCHEMBL23097495 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL20134162 | 0.74 | CTSK (0.42) | — | |
| SCHEMBL4118860 | 0.73 | TSHR (0.37) | TSHR | |
| SCHEMBL18250964 | 0.73 | L3MBTL1 (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298066-B1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | UNIV D'AVIGNON ET DES PAYS DE VAUCLUSE (FR) | 2019-08-07 | — | — | EP | disclosed |