Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21172113 | 0.86 | HDAC3 (0.46) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL409869 | 0.78 | ALDH1A1 (0.66) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL21187928 | 0.74 | KMT2A (0.46) | POLBKMT2AELANECYP1A2 | |
| SCHEMBL18993484 | 0.72 | HDAC3 (0.46) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL462670 | 0.72 | HDAC3 (0.53) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL18748394 | 0.71 | HDAC3 (0.52) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL28442493 | 0.69 | CES1 (0.47) | POLBKMT2AMEN1ELANETDP1 | |
| SCHEMBL4912246 | 0.68 | CES2 (0.45) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL6649148 | 0.68 | HDAC3 (0.58) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL5075256 | 0.68 | TDP1 (0.43) | ALDH1A1POLBKMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190241890-A1 | METHODS AND COMPOSITIONS FOR MANIPULATING TRANSLATION OF PROTEIN ISOFORMS FROM ALTERNATIVE INITIATION START SITES | SAREPTA THERAPEUTICS INC (US) | 2019-08-08 | — | — | US | disclosed |