Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19177310 | 0.81 | CASP2 (0.46) | ALDH1A1EPHX1MEN1KMT2ACASP2 | |
| SCHEMBL19861218 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL12660831 | 0.79 | HPGD (0.41) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21761154 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TP53MEN1KMT2ALMNA | |
| SCHEMBL24535363 | 0.77 | CASP2 (0.53) | POLBALDH1A1KMT2ACASP2HPGD | |
| SCHEMBL21538183 | 0.77 | MEN1 (0.56) | POLBALDH1A1EPHX1KDM4EMEN1 | |
| SCHEMBL23378480 | 0.76 | ALDH1A1 (0.30) | ALDH1A1CNR1 | |
| SCHEMBL16316312 | 0.76 | POLB (0.50) | POLBALDH1A1EPHX1KDM4ETP53 | |
| SCHEMBL23017806 | 0.74 | TDP1 (0.41) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2293893 | 0.74 | KDM4C (0.48) | POLBALDH1A1EPHX1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548975-B2 | Branched chimeric compounds, and methods of use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190240323-A1 | BRANCHED CHIMERIC COMPOUNDS, AND METHODS OF USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240323-A1 | BRANCHED CHIMERIC COMPOUNDS, AND METHODS OF USE THEREOF | PAICS, PBK, HAVCR2 | POLB 45/4885ALDH1A1 3972/4885EPHX1 3440/4885 |
| US-10548975-B2 | Branched chimeric compounds, and methods of use thereof | PAICS, PBK, HAVCR2 | POLB 45/4885ALDH1A1 3972/4885EPHX1 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.