Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861148 | 0.89 | SLC6A5 (0.38) | ALDH1A1SLC6A5MEN1KMT2ACASP2 | |
| SCHEMBL20076165 | 0.86 | CASP2 (0.43) | SLC6A5CASP2FFAR1CPT2TDP1 | |
| SCHEMBL12334732 | 0.85 | MEN1 (0.35) | ALDH1A1SLC6A5MEN1KMT2ACASP2 | |
| SCHEMBL19177310 | 0.83 | CASP2 (0.46) | ALDH1A1MEN1KMT2ACASP2FFAR1 | |
| SCHEMBL21761154 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ACASP2MCL1 | |
| SCHEMBL21236823 | 0.80 | POLB (0.36) | ALDH1A1MEN1KMT2ACASP2MCL1 | |
| SCHEMBL1963990 | 0.78 | HPGD (0.42) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL24943395 | 0.76 | ALDH1A1 (0.34) | ALDH1A1SLC6A5MEN1KMT2ACASP2 | |
| SCHEMBL12308380 | 0.76 | ALDH1A1 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL26731302 | 0.76 | PIK3CD (0.44) | ALDH1A1SLC6A5MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |