Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309772 | 0.76 | KMT2A (0.94) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL1309770 | 0.76 | KMT2A (0.94) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL3437935 | 0.73 | HPGD (0.61) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8675213 | 0.73 | HPGD (0.61) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL3437937 | 0.73 | HPGD (0.61) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL14972764 | 0.72 | KMT2A (0.66) | KMT2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL14972763 | 0.72 | KMT2A (0.66) | KMT2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL21238486 | 0.71 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL1310500 | 0.69 | KMT2A (0.60) | KMT2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL19043443 | 0.67 | KMT2A (0.57) | KMT2AALDH1A1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152946-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2019-08-08 | — | — | WO | disclosed |