Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21238503 | 0.76 | RAB9A (0.49) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL21238089 | 0.71 | KMT2A (0.61) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL3437935 | 0.69 | HPGD (0.61) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL3437937 | 0.69 | HPGD (0.61) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8675213 | 0.69 | HPGD (0.61) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL9682645 | 0.63 | RAB9A (0.49) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL9682651 | 0.63 | RAB9A (0.49) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL20601970 | 0.61 | RAB9A (0.51) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8154780 | 0.61 | RAB9A (0.51) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL11258728 | 0.61 | RAB9A (0.51) | ALDH1A1MAPTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152946-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2019-08-08 | — | — | WO | disclosed |