Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972764 | 1.00 | KMT2A (0.66) | KMT2ANAMPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1310500 | 0.91 | KMT2A (0.60) | KMT2ANAMPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1309772 | 0.80 | KMT2A (0.94) | KMT2AALDH1A1SMN1; SMN2L3MBTL1USP2 | |
| SCHEMBL1309770 | 0.80 | KMT2A (0.94) | KMT2AALDH1A1SMN1; SMN2L3MBTL1USP2 | |
| SCHEMBL1310955 | 0.78 | KMT2A (0.49) | KMT2ANAMPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1310328 | 0.78 | KMT2A (0.55) | KMT2ANAMPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1311593 | 0.76 | HSP90AA1 (0.56) | KMT2ANAMPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1310264 | 0.74 | ALDH1A1 (0.65) | KMT2AALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL14972765 | 0.74 | CYP1A2 (0.45) | KMT2AALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL3478318 | 0.74 | HSP90AA1 (0.54) | KMT2ANAMPTALDH1A1L3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |