Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.48 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885202 | 0.81 | GABRR1 (0.48) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL15436791 | 0.79 | GABRR1 (0.41) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL19074350 | 0.78 | PPARA (0.35) | TDP1 | |
| SCHEMBL5529299 | 0.74 | — | — | |
| SCHEMBL15171201 | 0.74 | — | — | |
| SCHEMBL1924283 | 0.74 | — | — | |
| Fluoride Ion SCHEMBL14121911 | 0.72 | GABRR1 (0.55) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL13450488 | 0.71 | — | — | |
| SCHEMBL14021800 | 0.70 | ALDH1A1 (0.32) | TSHR | |
| Fluoride Ion SCHEMBL14121503 | 0.70 | GABRR1 (0.52) | GABRR1GABRR2BLMGABRR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190240351-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS | MODERNATX, INC. | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240351-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS | POLRMT, MSH2, POLN | GABRR1 4040/4885GABRR2 3825/4885BLM 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.