Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.74 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21220656 | 0.99 | OPRM1 (0.73) | OPRM1OPRD1OPRK1ARRB1 | |
| Hydrochloric Acid SCHEMBL21220662 | 0.99 | OPRM1 (0.73) | OPRM1OPRD1OPRK1ARRB1 | |
| Hydrochloric Acid SCHEMBL21220658 | 0.99 | OPRM1 (0.73) | OPRM1OPRD1OPRK1ARRB1 | |
| SCHEMBL5399492 | 0.96 | OPRM1 (0.68) | OPRM1OPRD1OPRK1ARRB1 | |
| SCHEMBL5406264 | 0.90 | OPRM1 (0.66) | OPRM1OPRD1OPRK1ARRB1 | |
| SCHEMBL21221055 | 0.90 | OPRM1 (0.71) | OPRM1OPRK1 | |
| SCHEMBL21238057 | 0.90 | OPRM1 (0.71) | OPRM1OPRK1 | |
| SCHEMBL21221058 | 0.90 | OPRM1 (0.71) | OPRM1OPRK1 | |
| SCHEMBL21221052 | 0.90 | OPRM1 (0.71) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL21220800 | 0.89 | OPRM1 (0.69) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033394-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. | 2022-02-03 | — | — | US | disclosed |
| US-11180455-B2 | Compounds for the treatment of pain | ALKERMES, INC. | 2021-11-23 | — | — | US | disclosed |
| US-20200255383-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2020-08-13 | — | — | US | disclosed |
| WO-2019152946-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| US-20190241524-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241524-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | OPRK1, OPRL1, ACHE | OPRM1 7/4885OPRD1 4/4885OPRK1 1/4885 |
| US-11180455-B2 | Compounds for the treatment of pain | OPRK1, OPRL1, ACHE | OPRM1 7/4885OPRD1 4/4885OPRK1 1/4885 |
| US-20220033394-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | OPRK1, OPRL1, ACHE | OPRM1 7/4885OPRD1 4/4885OPRK1 1/4885 |
| US-20200255383-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | OPRK1, OPRL1, ACHE | OPRM1 7/4885OPRD1 4/4885OPRK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.