Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxilofrine SCHEMBL4256893 | 0.81 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL147458 | 0.81 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL14153976 | 0.81 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL14465574 | 0.81 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL5173040 | 0.81 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL20690347 | 0.81 | HIF1A (0.56) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL4713568 | 0.79 | ADRA1A (0.54) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL16144662 | 0.79 | HIF1A (0.55) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL5174274 | 0.79 | KMT2A (0.68) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL29354826 | 0.79 | KMT2A (0.68) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443127-A2 | COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS | Board of Regents, The University of Texas System (US) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010148191-A2 | COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-12-23 | — | — | WO | disclosed |