Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxilofrine SCHEMBL14153976 | 0.83 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL5173040 | 0.83 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL147458 | 0.83 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL4256893 | 0.83 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL14465574 | 0.83 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL2123890 | 0.81 | HIF1A (0.54) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL5174274 | 0.81 | KMT2A (0.68) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL4713568 | 0.81 | ADRA1A (0.54) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL16144662 | 0.81 | HIF1A (0.55) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL29354826 | 0.81 | KMT2A (0.68) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-24 | — | — | US | disclosed |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | HAX1, CYP2F1, CYP4X1 | HIF1A 3729/4885ADRA1A 1265/4885SLC6A2 1536/4885 |
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, CYP2S1, NAF1 | HIF1A 2966/4885ADRA1A 1111/4885SLC6A2 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.