Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 3/20 | 0.48 |
| ▸ | CDK9 | P50750 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | CHUK | O15111 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.42 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505977 | 0.86 | ERBB2 (0.44) | CCNT1CDK9MEN1ALDH1A1KMT2A | |
| SCHEMBL17456036 | 0.84 | CDK9 (0.48) | CCNT1CDK9MEN1ALDH1A1KMT2A | |
| SCHEMBL17455950 | 0.81 | CHRM3 (0.49) | MEN1ALDH1A1KMT2AIKBKBCHUK | |
| SCHEMBL17505978 | 0.79 | IKBKB (0.64) | IKBKBCHUKEPHX2 | |
| SCHEMBL17456016 | 0.77 | HRH1 (0.43) | IKBKBCHUKEPHX2 | |
| SCHEMBL21238750 | 0.77 | CDK9 (0.51) | CCNT1CDK9ERBB2GAKRIPK2 | |
| SCHEMBL17456031 | 0.77 | SMN1; SMN2 (0.49) | MEN1ALDH1A1KMT2AIKBKBCHUK | |
| SCHEMBL17455938 | 0.76 | SMN1; SMN2 (0.57) | MEN1KMT2A | |
| SCHEMBL13042338 | 0.75 | CHRM3 (0.76) | CHRM3 | |
| SCHEMBL17456052 | 0.74 | EPHX2 (0.51) | MEN1ALDH1A1KMT2AIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982666-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |