Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.64 |
| ▸ | CHUK | O15111 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.48 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.48 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456052 | 0.85 | EPHX2 (0.51) | IKBKBCHUKEPHX2RBP4 | |
| SCHEMBL17456070 | 0.84 | KDM1A (0.54) | IKBKBCHUKRBP4CACNB4CACNA1A | |
| SCHEMBL17456031 | 0.82 | SMN1; SMN2 (0.49) | IKBKBCHUKMAPK14 | |
| SCHEMBL17455950 | 0.79 | CHRM3 (0.49) | IKBKBCHUKEPHX2 | |
| SCHEMBL17456036 | 0.79 | CDK9 (0.48) | IKBKBCHUKEPHX2RBP4JAK2 | |
| SCHEMBL21238929 | 0.79 | CCNT1 (0.48) | IKBKBCHUKEPHX2 | |
| SCHEMBL15061997 | 0.78 | EPHX2 (0.59) | IKBKBCHUKEPHX2RBP4NAMPT | |
| SCHEMBL9013887 | 0.77 | IKBKB (0.49) | IKBKBCHUKEPHX2RBP4CACNB4 | |
| SCHEMBL17559489 | 0.76 | IKBKB (0.51) | IKBKBCHUKEPHX2NAMPTMAPK14 | |
| SCHEMBL17456016 | 0.75 | HRH1 (0.43) | IKBKBCHUKEPHX2NAMPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982666-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-02-10 | — | — | EP | disclosed |