Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 11/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21239469 | 1.00 | FPR2 (0.52) | FPR2L3MBTL1GAAMAPTTHRB | |
| SCHEMBL21239537 | 0.80 | FPR2 (0.77) | FPR2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL21239460 | 0.80 | FPR2 (0.77) | FPR2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL21239525 | 0.80 | FPR2 (0.57) | FPR2L3MBTL1GAAMAPTTHRB | |
| SCHEMBL21239461 | 0.80 | FPR2 (0.77) | FPR2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL21239484 | 0.80 | FPR2 (0.57) | FPR2GAAMAPTMEN1KMT2A | |
| SCHEMBL21239550 | 0.80 | FPR2 (0.57) | FPR2L3MBTL1GAAMAPTTHRB | |
| SCHEMBL21239463 | 0.80 | FPR2 (0.57) | FPR2GAAMAPTMEN1KMT2A | |
| SCHEMBL21239527 | 0.80 | FPR2 (0.57) | FPR2L3MBTL1GAAMAPTTHRB | |
| SCHEMBL21239464 | 0.80 | FPR2 (0.57) | FPR2GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206716-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-07-08 | — | — | US | claimed |
| EP-3524240-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-08-14 | — | — | EP | claimed |
| CN-109843283-B | Urea derivatives | 第一三共株式会社 | 2022-08-30 | — | — | CN | disclosed |
| US-20220144765-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20220144765-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20210206716-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-07-08 | — | — | US | disclosed |
| US-10968169-B2 | Urea derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-04-06 | — | — | US | disclosed |
| US-10968169-B2 | Urea derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-04-06 | — | — | US | disclosed |
| EP-3524240-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-08-14 | — | — | EP | disclosed |
| CN-109843283-A | Urea derivative | 第一三共株式会社 | 2019-06-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206716-A1 | UREA DERIVATIVE | IDO1, IDO2, TPH1 | FPR2 1882/4885L3MBTL1 3756/4885GAA 1221/4885 |
| US-10968169-B2 | Urea derivative | IDO1, IDO2, UTS2R | FPR2 2003/4885L3MBTL1 3946/4885GAA 1220/4885 |
| US-20220144765-A1 | UREA DERIVATIVE | IDO1, IDO2, TPH1 | FPR2 1882/4885L3MBTL1 3756/4885GAA 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.