Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25043591 | 0.81 | SLC6A2 (0.47) | SLC6A2LMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL5873468 | 0.76 | SLC6A4 (0.61) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL25971519 | 0.74 | SLC6A2 (0.44) | SLC6A2HRH1LMNAKCNH2CYP3A4 | |
| SCHEMBL11670635 | 0.74 | SLC6A4 (0.59) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL19030653 | 0.74 | CXCR3 (0.39) | HTR2AHTR2BKMT2A | |
| SCHEMBL21177760 | 0.72 | SLC6A4 (0.57) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL27600867 | 0.72 | SLC6A4 (0.52) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL1350229 | 0.71 | MEN1 (0.56) | MEN1KMT2ACYP19A1TSHRMAPK1 | |
| SCHEMBL27666403 | 0.71 | SLC6A4 (0.55) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL73498 | 0.71 | SLC6A4 (0.67) | SLC6A4SLC6A2HTR2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715595-B | Process for preparing cyclopropyl substituted acetophenones | 拜耳作物科学股份公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3523270-B1 | VERFAHREN ZUR HERSTELLUNG VON CYCLOPROPYL-SUBSTITUIERTEN ACETOPHENONEN | BAYER CROPSCIENCE AG (DE) | 2020-10-21 | — | — | EP | disclosed |
| US-10633321-B2 | Method for producing cyclopropyl-substituted acetophenones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-04-28 | — | — | US | disclosed |
| EP-3523270-A1 | METHOD FOR PRODUCING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-14 | — | — | EP | disclosed |
| CN-109715595-A | The method for preparing the acetophenone that cyclopropyl replaces | 拜耳作物科学股份公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-102603508-B | Preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone and intermediate thereof as well as preparation method of intermediate | JIANGSU CHENGYANG CROP TECHNOLOGY CO LTD | 2014-03-12 | — | — | CN | disclosed |
| CN-102603508-A | Preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone and intermediate thereof as well as preparation method of intermediate | JIANGSU CHENGYANG CROP TECHNOLOGY CO LTD | 2012-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633321-B2 | Method for producing cyclopropyl-substituted acetophenones | CYP21A2, CYP17A1, HSD17B7 | SLC6A4 1834/4885SLC6A2 2619/4885HTR2A 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.