Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241201 | 0.71 | CYP11B2 (0.39) | BRD4CYP11B2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21241223 | 0.71 | IDO1 (0.40) | BRD4CYP11B2ALDH1A1KDM4EPOLB | |
| SCHEMBL21233352 | 0.69 | CYP11B2 (0.43) | BRD4CYP11B2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21233158 | 0.69 | CYP11B2 (0.44) | BRD4CYP11B2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21241220 | 0.68 | BRD4 (0.46) | BRD4NISCHALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21233273 | 0.68 | CYP11B2 (0.39) | BRD4CYP11B2ALDH1A1KDM4EPOLB | |
| SCHEMBL21233272 | 0.67 | BRD4 (0.42) | BRD4CYP11B2ALDH1A1KDM4EPOLB | |
| SCHEMBL81650 | 0.66 | NISCH (0.59) | BRD4NISCHALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21233156 | 0.66 | CYP11B2 (0.43) | BRD4CYP11B2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21241208 | 0.66 | IDO1 (0.45) | BRD4CYP11B2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |