Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21233158 | 0.74 | CYP11B2 (0.44) | BRD4CYP11B2ALDH1A1 | |
| SCHEMBL21233275 | 0.70 | CYP11B2 (0.40) | BRD4CYP11B2ALDH1A1 | |
| SCHEMBL21241322 | 0.69 | NMT1 (0.41) | IDO1CYP11B2ALDH1A1FKBP5CYP3A4 | |
| SCHEMBL10053494 | 0.69 | PRMT5 (0.39) | BRD4CYP11B2ALDH1A1 | |
| SCHEMBL21241201 | 0.69 | CYP11B2 (0.39) | BRD4CYP11B2ALDH1A1 | |
| SCHEMBL21241222 | 0.69 | COMT (0.53) | IDO1BRD4CYP11B2ALDH1A1 | |
| SCHEMBL7194641 | 0.67 | IDO1 (0.59) | IDO1CYP11B2ALDH1A1FKBP5CYP3A4 | |
| SCHEMBL21233338 | 0.67 | CYP11B2 (0.51) | BRD4CYP11B2ALDH1A1CYP3A4 | |
| SCHEMBL21240976 | 0.67 | CYP11B2 (0.40) | BRD4CYP11B2ALDH1A1 | |
| SCHEMBL21233354 | 0.65 | CYP11B2 (0.42) | BRD4CYP11B2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |