Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952458 | 0.78 | CYP11B2 (0.31) | CYP11B2 | |
| SCHEMBL21233273 | 0.71 | CYP11B2 (0.39) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL21240968 | 0.71 | BRD4 (0.42) | CYP11B2BRD4CREBBPALDH1A1KDM4E | |
| SCHEMBL21241208 | 0.69 | IDO1 (0.45) | CYP11B2BRD4ALDH1A1 | |
| SCHEMBL21233172 | 0.68 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21241223 | 0.68 | IDO1 (0.40) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL13184124 | 0.66 | APOBEC3G (0.43) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL21233275 | 0.66 | CYP11B2 (0.40) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL21233158 | 0.66 | CYP11B2 (0.44) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL21240976 | 0.66 | CYP11B2 (0.40) | CYP11B2BRD4CREBBPPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |