Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 13/20 | 0.83 |
| ▸ | HSD17B2 | P37059 | 13/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940968 | 0.90 | HSD17B2 (0.72) | HSD17B1HSD17B2KDM4ELMNATSHR | |
| SCHEMBL10212283 | 0.90 | HSD17B2 (0.72) | HSD17B1HSD17B2KDM4ELMNATSHR | |
| SCHEMBL7374140 | 0.89 | HSD17B1 (0.71) | HSD17B1HSD17B2KDM4ELMNATSHR | |
| SCHEMBL94811 | 0.89 | HSD17B1 (0.71) | HSD17B1HSD17B2KDM4ELMNATSHR | |
| SCHEMBL21620298 | 0.89 | HSD17B1 (0.71) | HSD17B1HSD17B2LMNA | |
| SCHEMBL4658072 | 0.86 | HSD17B1 (0.68) | HSD17B1HSD17B2HTT | |
| SCHEMBL257767 | 0.84 | KMT2A (0.66) | HSD17B1HSD17B2KDM4EHTT | |
| SCHEMBL7376372 | 0.84 | HSD17B1 (0.64) | HSD17B1HSD17B2LMNATSHRSMN1; SMN2 | |
| SCHEMBL18774006 | 0.83 | HSD17B2 (0.60) | HSD17B1HSD17B2HSD17B10 | |
| SCHEMBL12938525 | 0.81 | HSD17B1 (0.57) | HSD17B1HSD17B2KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |