Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474766 | 0.87 | ATM (0.55) | HSD17B1HSD17B2ATMTSHRACHE | |
| SCHEMBL7368659 | 0.85 | ATM (0.57) | HSD17B1HSD17B2ATMKMT2AALDH1A1 | |
| SCHEMBL7379932 | 0.84 | ATM (0.75) | ATMMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21241029 | 0.84 | HSD17B1 (0.83) | HSD17B1HSD17B2TSHRSMN1; SMN2LMNA | |
| SCHEMBL7376601 | 0.83 | HSD17B2 (0.68) | HSD17B1HSD17B2ATMMEN1KMT2A | |
| SCHEMBL7375263 | 0.82 | ACHE (0.56) | ATMTSHRACHEMEN1KMT2A | |
| SCHEMBL29940968 | 0.81 | HSD17B2 (0.72) | HSD17B1HSD17B2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL10212283 | 0.81 | HSD17B2 (0.72) | HSD17B1HSD17B2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7374140 | 0.80 | HSD17B1 (0.71) | HSD17B1HSD17B2TSHRSMN1; SMN2LMNA | |
| SCHEMBL21620298 | 0.80 | HSD17B1 (0.71) | HSD17B1HSD17B2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |