Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 7/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179288 | 0.82 | GBA1 (0.62) | GBA1AOC3MYCTDP1HCAR3 | |
| SCHEMBL23183031 | 0.76 | GBA1 (0.50) | GBA1AOC3MYCTDP1HCAR3 | |
| SCHEMBL21388440 | 0.76 | HCAR3 (0.50) | GBA1AOC3MYCHCAR3HDAC6 | |
| SCHEMBL11567147 | 0.73 | GBA1 (0.47) | GBA1AOC3MEN1KMT2A | |
| SCHEMBL20056973 | 0.72 | HCAR3 (0.57) | GBA1AOC3HCAR3HDAC6CCR1 | |
| SCHEMBL18937028 | 0.71 | GBA1 (0.45) | GBA1AOC3MYCTDP1HCAR3 | |
| SCHEMBL8278724 | 0.70 | CCR1 (0.48) | GBA1AOC3TDP1HCAR3HDAC6 | |
| SCHEMBL8224262 | 0.69 | HDAC6 (0.39) | GBA1TDP1HCAR3HDAC6CCR1 | |
| SCHEMBL12394221 | 0.69 | HCAR3 (0.46) | GBA1AOC3HCAR3HDAC6CCR1 | |
| SCHEMBL11567387 | 0.69 | GBA1 (0.48) | GBA1KDM4EMEN1KMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |