Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228035 | 0.78 | GBA1 (0.59) | GBA1CHKAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL179288 | 0.76 | GBA1 (0.62) | HDAC6CCR1CCR5CCR8GBA1 | |
| SCHEMBL20056973 | 0.73 | HCAR3 (0.57) | HDAC6CCR1CCR5CCR8GBA1 | |
| SCHEMBL7242158 | 0.71 | CCR1 (0.43) | HDAC6CCR1CCR5CCR8NOS3 | |
| SCHEMBL23183031 | 0.70 | GBA1 (0.50) | HDAC6CCR1CCR5CCR8GBA1 | |
| SCHEMBL12394221 | 0.70 | HCAR3 (0.46) | HDAC6CCR1CCR5CCR8GBA1 | |
| SCHEMBL21388440 | 0.70 | HCAR3 (0.50) | HDAC6CCR1CCR5CCR8GBA1 | |
| SCHEMBL544100 | 0.70 | ALDH1A1 (0.48) | C5AR1CRHR1CHKACNR1CNR2 | |
| SCHEMBL175241 | 0.69 | CHRM2 (0.44) | ADRA2AADRA2BADRA2CMAPTRAB9A | |
| SCHEMBL21241060 | 0.69 | GBA1 (0.45) | HDAC6CCR1CCR5CCR8GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569701-B1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 2000-09-27 | — | — | EP | claimed |
| US-5463065-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| US-5332824-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | claimed |
| EP-0569701-A1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 1993-11-18 | — | — | EP | claimed |
| EP-0569701-B1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 2000-09-27 | — | — | EP | disclosed |
| US-5463065-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5463065-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5332824-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| EP-0569701-A1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569701-A1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |