Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952465 | 0.78 | HIF1A (0.33) | CYP11B2KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL21240976 | 0.73 | CYP11B2 (0.40) | CYP11B2KDM4EALDH1A1BRD4GAA | |
| SCHEMBL21233194 | 0.71 | CYP11B2 (0.42) | CYP11B2KDM4EALDH1A1BRD4HIF1A | |
| SCHEMBL30574716 | 0.71 | KDR (0.39) | BRD4HIF1ACREBBP | |
| SCHEMBL21233344 | 0.69 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21233196 | 0.69 | CYP11B2 (0.47) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL21233198 | 0.68 | CYP11B2 (0.39) | CYP11B2KDM4EALDH1A1BRD4GAA | |
| SCHEMBL21233199 | 0.68 | POLB (0.42) | CYP11B2KDM4EALDH1A1BRD4GAA | |
| SCHEMBL16658812 | 0.68 | GAA (0.47) | CYP11B2KDM4EALDH1A1GAAPRMT5 | |
| SCHEMBL21233273 | 0.68 | CYP11B2 (0.39) | CYP11B2KDM4EALDH1A1BRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |