Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21233271 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL22952414 | 0.77 | KDM4E (0.33) | CYP11B2KDM4EALDH1A1 | |
| SCHEMBL21241158 | 0.73 | CYP11B2 (0.39) | CYP11B2BRD4KDM4EALDH1A1MAPK1 | |
| SCHEMBL21233337 | 0.70 | KDM4E (0.47) | CYP11B2BRD4KDM4EALDH1A1MAPK1 | |
| SCHEMBL21233346 | 0.70 | BRD4 (0.43) | CYP11B2BRD4KDM4EALDH1A1MAPK1 | |
| SCHEMBL27157217 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1POLB | |
| SCHEMBL21233194 | 0.69 | CYP11B2 (0.42) | CYP11B2BRD4KDM4EALDH1A1MAPK1 | |
| SCHEMBL21233269 | 0.69 | CYP11B2 (0.39) | CYP11B2BRD4KDM4EALDH1A1MAPK1 | |
| SCHEMBL15345069 | 0.69 | CCR1 (0.55) | CYP11B2BRD4KDM4EALDH1A1MAPK1 | |
| SCHEMBL31424344 | 0.68 | ALDH1A1 (0.32) | BRD4ALDH1A1CREBBPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |