Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.58 |
| ▸ | NOS2 | P35228 | 4/20 | 0.58 |
| ▸ | NOS1 | P29475 | 3/20 | 0.58 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91466 | 0.83 | NOS3 (0.58) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL29637494 | 0.82 | NOS3 (0.44) | NOS3NOS2NOS1P2RX3P2RX2 | |
| SCHEMBL29637497 | 0.82 | NOS3 (0.44) | NOS3NOS2NOS1P2RX3P2RX2 | |
| SCHEMBL2894993 | 0.82 | NOS3 (0.44) | NOS3NOS2NOS1P2RX3P2RX2 | |
| SCHEMBL23882539 | 0.80 | NOS3 (0.50) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL4142773 | 0.77 | UHRF1 (0.48) | P2RX3P2RX2ALDH1A1TAAR1PDGFRB | |
| SCHEMBL22491094 | 0.77 | GAA (0.50) | NOS3NOS2NOS1P2RX3P2RX2 | |
| SCHEMBL23068062 | 0.77 | P2RX3 (0.43) | NOS3NOS2NOS1P2RX3P2RX2 | |
| SCHEMBL27485620 | 0.76 | NNMT (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21223488 | 0.75 | HSD17B10 (0.49) | NOS3NOS2NOS1DHFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023056441-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-04-06 | — | — | WO | disclosed |
| WO-2021050824-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |