SCHEMBL21241276

SCHEMBL21241276

NNC(=O)c1ccc2cc(C(N)=O)ccc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 8/20 0.62
LCK P06239 1/20 0.60
PLG P00747 3/20 0.54
F2 P00734 2/20 0.54
KLKB1 P03952 2/20 0.54
PRSS1 P07477 2/20 0.54
MPO P05164 1/20 0.50
CYP3A4 P08684 1/20 0.50
KDM5A P29375 1/20 0.50
BLM P54132 1/20 0.50
GFER P55789 1/20 0.50
PMP22 Q01453 1/20 0.50
HIF1A Q16665 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MAPT P10636 3/20 0.48
OGG1 O15527 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL808434 0.92 MPO (0.58) PLAUPLGF2KLKB1PRSS1
SCHEMBL9648378 0.85 MPO (0.56) PLAULCKMPOCYP3A4KDM5A
SCHEMBL2363489 0.85 LCK (0.78) PLAULCKPLGF2KLKB1
SCHEMBL1149678 0.84 NPC1 (0.62) KDM4EALDH1A1MAPTNPC1
SCHEMBL28810616 0.84 NR1H4 (0.53) PLAUPLGF2KLKB1PRSS1
SCHEMBL1707304 0.82 GFER (0.64) PLAUMPOCYP3A4KDM5ABLM
Hydrochloric Acid SCHEMBL20299655 0.82 NPC1 (0.60) KDM4EALDH1A1MAPTNPC1
SCHEMBL3028425 0.82 PLAU (0.74) PLAULCKPLGF2KLKB1
SCHEMBL18448812 0.82 ALDH1A1 (0.66) PLAUMPOCYP3A4KDM5ABLM
SCHEMBL18951239 0.81 CYP2A6 (0.55) PLAUMPOCYP3A4KDM5ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3125033-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2021-06-02 EP disclosed
EP-3133136-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-08-07 EP disclosed