SCHEMBL1707304

SCHEMBL1707304

NNC(=O)c1ccc2cc(O)ccc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.64
BLM P54132 2/20 0.64
MPO P05164 1/20 0.64
CYP3A4 P08684 1/20 0.64
KDM5A P29375 1/20 0.64
PMP22 Q01453 1/20 0.64
HIF1A Q16665 1/20 0.64
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 3/20 0.61
F12 P00748 1/20 0.53
NPC1 O15118 2/20 0.53
CLK1 P49759 2/20 0.53
DYRK1A Q13627 2/20 0.53
DYRK1B Q9Y463 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
RAB9A P51151 1/20 0.53
DEGS1 O15121 2/20 0.51
MAPT P10636 4/20 0.49
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5693969 0.98 GFER (0.62) GFERBLMMPOCYP3A4KDM5A
SCHEMBL808434 0.90 MPO (0.58) GFERBLMMPOCYP3A4KDM5A
SCHEMBL9648378 0.84 MPO (0.56) GFERBLMMPOCYP3A4KDM5A
SCHEMBL1149678 0.82 NPC1 (0.62) ALDH1A1KDM4ENPC1MEN1KMT2A
SCHEMBL21241276 0.82 PLAU (0.62) GFERBLMMPOCYP3A4KDM5A
SCHEMBL28810616 0.82 NR1H4 (0.53) GFERBLMMPOCYP3A4KDM5A
SCHEMBL14880024 0.82 KDM4E (0.60) KDM4EF12NPC1CLK1DYRK1A
SCHEMBL6010047 0.81 F12 (0.55) GFERBLMMPOCYP3A4KDM5A
Hydrochloric Acid SCHEMBL20299655 0.81 NPC1 (0.60) ALDH1A1KDM4ENPC1MEN1KMT2A
SCHEMBL13422491 0.80 NPC1 (0.56) CYP3A4HIF1AALDH1A1KDM4EF12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112341372-A Reactive non-extraction anti-aging agent and preparation method thereof 黄淮学院 2021-02-09 CN claimed
EP-1732896-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) Aventis Pharmaceuticals Inc. (US) 2006-12-20 EP claimed
WO-2005097750-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) AVENTIS PHARMACEUTICALS INC. (US) 2005-10-20 WO claimed
CN-113754983-B Resin composition 旭化成株式会社 2024-12-06 CN disclosed
CN-112341372-B Reactive anti-aging agent without extraction and preparation method thereof 黄淮学院 2023-10-24 CN disclosed
US-11643543-B2 Resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-05-09 US disclosed
CN-110643139-B Resin composition 旭化成株式会社 2022-07-15 CN disclosed
CN-110003609-B Resin composition 旭化成株式会社 2022-06-24 CN disclosed
CN-110003610-B Resin composition 旭化成株式会社 2022-06-24 CN disclosed
US-20220040353-A1 DEODORANT-CONTAINING WORKING FLUID, METHOD FOR MANUFACTURING DEODORIZING PRODUCT, DEODORIZING FILTER MEDIUM, DEODORIZING FILTER UNIT, AND DEODORIZING DEVICE TOAGOSEI CO., LTD. (JP) 2022-02-10 US disclosed
US-20210380798-A1 RESIN COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-12-09 US disclosed
US-20070073007-A1 Polyacetal resin composition and molded article thereof POLYPLASTICS CO., LTD. (JP) 2007-03-29 US disclosed
EP-1522554-B1 Polyacetal resin composition and shaped article thereof POLYPLASTICS CO (JP) 2006-11-22 EP disclosed
EP-1688461-A1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Polyplastics Co., Ltd. (JP) 2006-08-09 EP disclosed
EP-1683838-A1 ALDEHYDE INHIBITOR COMPOSITION AND POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-26 EP disclosed
EP-1679346-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-12 EP disclosed
US-20060122428-A1 Hydroxynaphthoic acid hydrazide compound and method for preparing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2006-06-08 US disclosed
CN-1772730-A Hydroxynaphthoic acid hydrazide compounds and method for preparing the same UENO SEIYAKU OYO KENKYUJO KK (JP) 2006-05-17 CN disclosed
EP-1655282-A1 Hydroxynaphthoic acid hydrazide compounds and method for preparing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2006-05-10 EP disclosed
EP-1522554-A1 Polyacetal resin composition and shaped article thereof Polyplastics Co., Ltd. (JP) 2005-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122428-A1 Hydroxynaphthoic acid hydrazide compound and method for preparing the same HADH, HAAO, HAGH GFER 888/4885BLM 4277/4885MPO 1517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.