SCHEMBL21241344

SCHEMBL21241344

Cc1ccc(Cc2cccnc2)nc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2A6 P11509 1/20 0.49
CHRNB2 P17787 3/20 0.44
CHRNA4 P43681 3/20 0.44
TBXAS1 P24557 3/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
HRH4 Q9H3N8 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CHRNA7 P36544 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18525559 0.89 CYP11B1 (0.51) ALDH1A1TBXAS1CYP11B1CYP11B2L3MBTL1
SCHEMBL18569707 0.85 CYP1A2 (0.63) ALDH1A1CYP3A4CYP2A6CHRNB2CHRNA4
SCHEMBL13562421 0.82 ALDH1A1 (0.46) ALDH1A1CYP3A4CYP2D6KDM4E
SCHEMBL20684755 0.80 KEAP1 (0.41) CYP3A4CYP2A6CYP11B1CYP11B2HRH4
SCHEMBL19034706 0.79 CYP1A2 (0.46) CYP3A4CHRNB2CHRNA4TBXAS1CYP11B1
SCHEMBL5780182 0.78 ALDH1A1 (0.59) ALDH1A1CHRNB2CHRNA4TBXAS1CYP11B1
SCHEMBL20156878 0.78 CYP2A6 (0.50) ALDH1A1CYP2A6CHRNB2CHRNA4TBXAS1
SCHEMBL25140240 0.78 L3MBTL1 (0.52) ALDH1A1CYP3A4CYP2A6CYP1A2CYP2D6
SCHEMBL18622091 0.77 KEAP1 (0.50) ALDH1A1CYP2A6CYP1A2KDM4ETDP1
SCHEMBL14573460 0.77 CCR1 (0.52) ALDH1A1CYP3A4CYP2A6KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019149260-A1 PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2019-08-08 WO disclosed