Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126360 | 0.92 | SERPINE1 (0.45) | SERPINE1PANK3ALDH1A1LMNAHTT | |
| SCHEMBL2125848 | 0.91 | SERPINE1 (0.37) | SERPINE1TMEM97PANK3SIRT6HDAC3 | |
| SCHEMBL2127741 | 0.90 | PANK3 (0.34) | SERPINE1PANK3ALDH1A1LMNACYP1A2 | |
| SCHEMBL2128389 | 0.85 | SERPINE1 (0.45) | SERPINE1PANK3ALDH1A1LMNAHTT | |
| SCHEMBL2126718 | 0.85 | CCNC (0.40) | TMEM97SIRT6HDAC3HDAC1HDAC2 | |
| SCHEMBL2125553 | 0.85 | SERPINE1 (0.36) | SERPINE1TMEM97PANK3SIRT6HDAC3 | |
| SCHEMBL15740360 | 0.85 | TMEM97 (0.36) | TMEM97SIRT6ARCES2ABCB11 | |
| SCHEMBL15740495 | 0.83 | HRH3 (0.34) | TMEM97SIRT6ARCES2ABCB11 | |
| SCHEMBL15740426 | 0.83 | HRH3 (0.42) | SERPINE1TMEM97SIRT6MAPK1HRH3 | |
| SCHEMBL15740411 | 0.83 | HRH3 (0.37) | TMEM97SIRT6ARCES2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |