Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740426 | 0.91 | HRH3 (0.42) | TMEM97HRH3SIRT6MAPK1 | |
| SCHEMBL15740495 | 0.91 | HRH3 (0.34) | TMEM97HRH3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15740367 | 0.91 | LMNA (0.34) | TMEM97HRH3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15740411 | 0.91 | HRH3 (0.37) | TMEM97HRH3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2126360 | 0.85 | SERPINE1 (0.45) | HRH3ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2125848 | 0.85 | SERPINE1 (0.37) | TMEM97ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2124155 | 0.85 | SERPINE1 (0.37) | TMEM97HRH3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15740370 | 0.84 | POLB (0.37) | TMEM97SMN1; SMN2KDM4EPOLB | |
| SCHEMBL15740364 | 0.82 | SIRT6 (0.41) | TMEM97ALDH1A1LMNASMN1; SMN2SIRT6 | |
| SCHEMBL15740464 | 0.82 | SIRT6 (0.41) | TMEM97ALDH1A1LMNASMN1; SMN2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |