Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126360 | 0.93 | SERPINE1 (0.45) | SERPINE1MEN1KMT2AHRH3MAPT | |
| SCHEMBL2125553 | 0.92 | SERPINE1 (0.36) | SERPINE1MAPTKDM4EPANK3SMN1; SMN2 | |
| SCHEMBL2127941 | 0.88 | MEN1 (0.39) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL2126153 | 0.87 | SERPINE1 (0.48) | SERPINE1MEN1KMT2AHRH3KDM4E | |
| SCHEMBL2127785 | 0.86 | CCNC (0.40) | HRH3MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2124155 | 0.85 | SERPINE1 (0.37) | SERPINE1MEN1KMT2AHRH3PANK3 | |
| SCHEMBL2125848 | 0.85 | SERPINE1 (0.37) | SERPINE1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2127365 | 0.83 | SIRT6 (0.39) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL15740426 | 0.82 | HRH3 (0.42) | SERPINE1HRH3 | |
| SCHEMBL2119695 | 0.81 | SERPINE1 (0.47) | SERPINE1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |