Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124155 | 0.90 | SERPINE1 (0.37) | PANK3MAPK1ALDH1A1SERPINE1GLA | |
| SCHEMBL2126360 | 0.82 | SERPINE1 (0.45) | PANK3MAPTGAAALDH1A1SERPINE1 | |
| SCHEMBL2119676 | 0.81 | PANK3 (0.40) | PANK3MAPTMAPK1GAAALDH1A1 | |
| SCHEMBL2617773 | 0.81 | PANK3 (0.40) | PANK3MAPTMAPK1GAAALDH1A1 | |
| SCHEMBL2617893 | 0.81 | PANK3 (0.40) | PANK3MAPTMAPK1GAAALDH1A1 | |
| SCHEMBL2125848 | 0.81 | SERPINE1 (0.37) | PANK3MAPTMAPK1ALDH1A1SERPINE1 | |
| SCHEMBL2128389 | 0.75 | SERPINE1 (0.45) | PANK3MAPTGAAALDH1A1SERPINE1 | |
| SCHEMBL2126718 | 0.75 | CCNC (0.40) | MAPTMAPK1GAAALDH1A1GLA | |
| SCHEMBL15740360 | 0.75 | TMEM97 (0.36) | MAPK1ALDH1A1GLALMNACYP1A2 | |
| SCHEMBL2125553 | 0.75 | SERPINE1 (0.36) | PANK3MAPTMAPK1ALDH1A1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |