Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004872 | 0.84 | DEGS1 (0.39) | KDM1ACES2CES1AKT1MAPK1 | |
| SCHEMBL19018493 | 0.79 | KDM1A (0.37) | KDM1ACES2CES1AKT1MAPK1 | |
| SCHEMBL16871633 | 0.78 | TPMT (0.37) | CA1CA2 | |
| SCHEMBL13951010 | 0.77 | CES2 (0.43) | KDM1ACES2CES1AKT1MAPK1 | |
| SCHEMBL19842063 | 0.75 | LMNA (0.34) | CES2CES1AKT1MAPK1LMNA | |
| SCHEMBL18481818 | 0.74 | KDM1A (0.33) | KDM1A | |
| SCHEMBL24016382 | 0.74 | L3MBTL1 (0.33) | CES2CES1AKT1MAPK1LMNA | |
| SCHEMBL19052049 | 0.73 | KDM1A (0.45) | KDM1ACES2CES1AKT1MAPK1 | |
| SCHEMBL14028062 | 0.73 | KDM1A (0.45) | KDM1ACES2CES1AKT1MAPK1 | |
| SCHEMBL3237816 | 0.73 | KDM1A (0.50) | KDM1ACES2CES1AKT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692028-B1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 30 | FORMA THERAPEUTICS INC (US) | 2023-04-26 | — | — | EP | disclosed |
| EP-3269791-B1 | IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION | UNIVERSAL DISPLAY CORP (US) | 2019-08-07 | — | — | EP | disclosed |