SCHEMBL21242225

SCHEMBL21242225

Oc1ccc(/N=N/c2ccc(-c3ccc(-c4ccc(/N=N/c5ccc(O)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.67
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
ESR1 P03372 3/20 0.65
ESR2 Q92731 1/20 0.65
GLB1 P16278 1/20 0.64
CTRB1 P17538 1/20 0.64
CTRC Q99895 1/20 0.64
MAPT P10636 3/20 0.54
EGFR P00533 1/20 0.54
MMP3 P08254 1/20 0.52
BCL2L1 Q07817 1/20 0.52
RAB9A P51151 3/20 0.52
CA12 O43570 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA7 P43166 1/20 0.52
HSP90AA1 P07900 1/20 0.52
ABL1 P00519 1/20 0.50
ABCB1 P08183 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12534430 1.00 NPC1 (0.67) NPC1MEN1KMT2AESR1ESR2
SCHEMBL901189 0.91 NPC1 (0.78) NPC1MEN1KMT2AESR1ESR2
SCHEMBL901190 0.91 NPC1 (0.78) NPC1MEN1KMT2AESR1ESR2
SCHEMBL9367894 0.91 NPC1 (0.78) NPC1MEN1KMT2AESR1ESR2
SCHEMBL9367899 0.91 NPC1 (0.78) NPC1MEN1KMT2AESR1ESR2
SCHEMBL3464588 0.90 MEN1 (0.86) NPC1MEN1KMT2AESR1ESR2
SCHEMBL12534484 0.88 ACHE (0.59) NPC1MEN1KMT2AESR1ESR2
SCHEMBL21242228 0.86 MAPT (0.53) NPC1MEN1KMT2AESR1ESR2
Biphenyl SCHEMBL27775490 0.85 MEN1 (0.86) NPC1MEN1KMT2AESR1ESR2
SCHEMBL9316062 0.82 MMP3 (0.76) NPC1MEN1KMT2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442931-B2 Dye compound, composition comprising dye compound, and display device using dye compound SAMSUNG DISPLAY CO. LTD. (KR) 2019-10-15 US disclosed
EP-3412734-B1 DYE COMPOUND, COMPOSITION COMPRISING THE DYE COMPOUND, AND DISPLAY DEVICE USING THE DYE COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2019-08-07 EP disclosed