SCHEMBL901189

SCHEMBL901189

Oc1ccc(/N=N/c2ccc(O)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.78
MEN1 O00255 3/20 0.78
KMT2A Q03164 3/20 0.78
GLB1 P16278 1/20 0.74
CTRB1 P17538 1/20 0.74
CTRC Q99895 1/20 0.74
MAPT P10636 3/20 0.61
EGFR P00533 1/20 0.61
CA12 O43570 4/20 0.58
CA2 P00918 4/20 0.58
CA9 Q16790 4/20 0.58
RAB9A P51151 4/20 0.58
CA7 P43166 1/20 0.58
HSP90AA1 P07900 1/20 0.58
CA1 P00915 3/20 0.57
LMNA P02545 2/20 0.57
HPGD P15428 2/20 0.57
NFKB1 P19838 2/20 0.57
KDM4E B2RXH2 1/20 0.57
GMNN O75496 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9367894 1.00 NPC1 (0.78) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL901190 1.00 NPC1 (0.78) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL9367899 1.00 NPC1 (0.78) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL21242225 0.91 NPC1 (0.67) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL12534430 0.91 NPC1 (0.67) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL1985759 0.88 MEN1 (1.00) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL1198024 0.88 MEN1 (1.00) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL156633 0.88 MEN1 (1.00) NPC1MEN1KMT2AGLB1CTRB1
SCHEMBL20580111 0.88 MEN1 (1.00) NPC1MEN1KMT2AGLB1CTRB1
Azobenzene SCHEMBL27882900 0.88 MEN1 (1.00) NPC1MEN1KMT2AGLB1CTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063716-A Anti-fatigue mechanical interlocking light response supermolecular hydrogel and preparation method thereof 华东师范大学 2024-05-24 CN claimed
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN claimed
CN-116478063-A Azobenzene monomer, high-strength low-friction coefficient shape memory polymer material with light response performance, preparation method and application 中国科学院兰州化学物理研究所 2023-07-25 CN claimed
CN-116284685-A Recyclable shape memory liquid crystal epoxy resin and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-06-23 CN claimed
CN-115505350-A Acrylic pressure-sensitive adhesive tape and preparation method thereof 广东皇冠新材料科技有限公司 2022-12-23 CN claimed
US-20220235343-A1 NOVEL ADP-RIBOSYL CYCLASE AND INHIBITOR THEREOF INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY (KR) 2022-07-28 US claimed
EP-3992284-A1 NOVEL ADP-RIBOSYL CYCLASE AND INHIBITOR THEREOF Industrial Cooperation Foundation Chonbuk National University (KR) 2022-05-04 EP claimed
CN-114269910-A Novel adenosine diphosphate ribocyclase and inhibitor thereof 全北大学校产学协力团 2022-04-01 CN claimed
CN-109971009-B Preparation method and application of photoresponse unsupported thin film 青岛科技大学 2021-10-01 CN claimed
CN-110433294-B Azobenzene-based hypoxic responsive micelle and preparation method and application thereof 同济大学 2021-06-08 CN claimed
EP-2102149-A1 STILBENE DERIVATIVES FOR ADP-RIBOSYL CYCLASE INHIBITORS Industrial Cooperation Foundation Chonbuk National University (KR) 2009-09-23 EP claimed
WO-2008082169-A1 STILBENE DERIVATIVES FOR ADP-RIBOSYL CYCLASE INHIBITORS INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY (KR) 2008-07-10 WO claimed
EP-0379058-B1 Vinyl ester resins containing mesogenic/rigid rodlike moieties DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US claimed
US-5164464-A Liquid crystalline polymers, acrylated epoxy resins THE DOW CHEMICAL COMPANY (US) 1992-11-17 US claimed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US claimed
EP-0379058-A2 Vinyl ester resins containing mesogenic/rigid rodlike moieties THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220235343-A1 NOVEL ADP-RIBOSYL CYCLASE AND INHIBITOR THEREOF CD38, ADCY2, ADPRS NPC1 3865/4885MEN1 3675/4885KMT2A 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.