Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062781 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TSHRCYP2C19MEN1 | |
| SCHEMBL477423 | 0.78 | HDAC4 (0.38) | HTTALDH1A1SMN1; SMN2TSHRCYP2C19 | |
| SCHEMBL2480644 | 0.77 | NPSR1 (0.36) | ALDH1A1SMN1; SMN2TSHRCYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL4731891 | 0.76 | HDAC4 (0.37) | HTTALDH1A1SMN1; SMN2TSHRCYP2C19 | |
| SCHEMBL20069554 | 0.76 | CYP1A2 (0.37) | ALDH1A1POLBCYP1A2 | |
| SCHEMBL29109148 | 0.75 | HTT (0.42) | HTTALDH1A1SMN1; SMN2CYP2C19MEN1 | |
| SCHEMBL5219364 | 0.73 | HTT (0.41) | HTTALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL11955648 | 0.73 | HTT (0.41) | HTTALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL14627310 | 0.73 | HTT (0.41) | HTTALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL4214365 | 0.73 | HTT (0.41) | HTTALDH1A1SMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521289-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | Effector Therapeutics Inc. (US) | 2019-08-07 | — | — | EP | disclosed |