SCHEMBL21242465

SCHEMBL21242465

Cc1cc(F)ccc1/N=N/c1ccc(NCCNc2ccc(/N=N/c3ccc(F)cc3C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.41
KMT2A Q03164 10/20 0.41
NPC1 O15118 9/20 0.41
RAB9A P51151 9/20 0.41
MEN1 O00255 8/20 0.41
TDP1 Q9NUW8 6/20 0.41
MAPK1 P28482 5/20 0.41
L3MBTL1 Q9Y468 5/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
MMP14 P50281 1/20 0.41
BRD4 O60885 2/20 0.40
THRB P10828 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19648780 0.84 BRD4 (0.44) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242325 0.83 MAPT (0.43) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242247 0.83 EGFR (0.47) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242244 0.80 MAPT (0.36) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242324 0.79 MAPT (0.44) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242740 0.79 TRPA1 (0.41) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242466 0.78 THRB (0.46) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL21242464 0.74 MEN1 (0.44) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL19648595 0.73 BRD4 (0.47) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL12071022 0.72 RAB9A (0.48) MAPTKMT2ANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3412734-B1 DYE COMPOUND, COMPOSITION COMPRISING THE DYE COMPOUND, AND DISPLAY DEVICE USING THE DYE COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2019-08-07 EP disclosed