Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263820 | 0.91 | NPC1 (0.83) | NPC1RAB9AATMPTPN1SMN1; SMN2 | |
| SCHEMBL8660366 | 0.91 | NPC1 (0.83) | NPC1RAB9AATMPTPN1SMN1; SMN2 | |
| SCHEMBL4113542 | 0.88 | MAPT (0.72) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9767723 | 0.87 | NPC1 (0.76) | NPC1RAB9APTPN1SMN1; SMN2KMT2A | |
| SCHEMBL10939703 | 0.87 | NPC1 (0.76) | NPC1RAB9APTPN1SMN1; SMN2KMT2A | |
| SCHEMBL611657 | 0.87 | NPC1 (0.76) | NPC1RAB9APTPN1SMN1; SMN2KMT2A | |
| SCHEMBL27846423 | 0.86 | NPC1 (0.71) | NPC1RAB9AATMPTPN1SMN1; SMN2 | |
| SCHEMBL196916 | 0.85 | CA1 (0.64) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11122035 | 0.85 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2121351 | 0.85 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730980-A | Compound and stereoisomer thereof, or pharmaceutically acceptable salt and application thereof | 合肥工业大学智能制造技术研究院 | 2023-09-12 | — | — | CN | disclosed |
| EP-3049387-B1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & CO (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3049388-B1 | NUCLEATING AGENT FOR THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & CO (US) | 2019-08-07 | — | — | EP | disclosed |
| CN-103319371-A | Preparation method and application of N-substituted hydroxamic acid compound | UNIV LANGZHOU | 2013-09-25 | — | — | CN | disclosed |