SCHEMBL21243360

SCHEMBL21243360

O=C(OCC1CCCCC1)C1C2CCC(C2)C1C(=O)OCC1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
PARP15 Q460N3 3/20 0.39
PARP10 Q53GL7 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 2/20 0.38
TP53 P04637 1/20 0.38
SLC1A3 P43003 3/20 0.38
SLC1A2 P43004 3/20 0.38
SLC1A1 P43005 3/20 0.38
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
PARP2 Q9UGN5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13762649 0.83 ALDH1A1 (0.41) LMNAALDH1A1MEN1CYP1A2CYP2C9
SCHEMBL21243344 0.81 ALDH1A1 (0.40) LMNAPARP15PARP10ALDH1A1MEN1
SCHEMBL21243355 0.81 ALDH1A1 (0.40) LMNAPARP15PARP10ALDH1A1MEN1
SCHEMBL13197292 0.80 LMNA (0.54) LMNAPARP15PARP10ALDH1A1CYP3A4
SCHEMBL21243373 0.79 TLR4 (0.39) LMNAALDH1A1MEN1CYP1A2CYP2C9
SCHEMBL13197300 0.79 LMNA (0.44) LMNAPARP15PARP10ALDH1A1MEN1
SCHEMBL15911852 0.79 LMNA (0.44) LMNAPARP15PARP10ALDH1A1MEN1
SCHEMBL14422655 0.78 LMNA (0.53) LMNAPARP15PARP10ALDH1A1CYP3A4
SCHEMBL21243359 0.78 TP53 (0.60) LMNAPARP15PARP10KMT2ACYP3A4
SCHEMBL11281608 0.78 LMNA (0.53) LMNAPARP15PARP10ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947472-B2 Lubricant base oil for power transmission NEW JAPAN CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION NEW JAPAN CHEMICAL CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947472-B2 Lubricant base oil for power transmission DNAH12, DYNC1LI1, DYNC1LI2 LMNA 2553/4885PARP15 596/4885PARP10 785/4885
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION DNAH12, DYNC1LI1, DYNC1LI2 LMNA 2553/4885PARP15 596/4885PARP10 785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.