SCHEMBL21243363

SCHEMBL21243363

CCCCC1CCC(COC(=O)C2C3CCC(C3)C2C(=O)OCC2CCC(CCCC)CC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
CYP1A2 P05177 2/20 0.39
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 2/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
GAA P10253 1/20 0.36
NAAA Q02083 1/20 0.36
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
PKM P14618 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243373 0.90 TLR4 (0.39) MAPTCYP1A2LMNAMAPK1ALDH1A1
SCHEMBL21243344 0.83 ALDH1A1 (0.40) CYP1A2HTTLMNAALDH1A1MEN1
SCHEMBL21243355 0.80 ALDH1A1 (0.40) CYP1A2LMNAALDH1A1MEN1KMT2A
SCHEMBL21243334 0.79 CYP1A2 (0.48) MAPTCYP1A2POLBHPGDHTT
SCHEMBL21243350 0.79 LIPA (0.41) MAPTCYP1A2HTTALDH1A1MEN1
SCHEMBL21243369 0.79 HTT (0.39) MAPTCYP1A2POLBHPGDHTT
SCHEMBL13762649 0.78 ALDH1A1 (0.41) CYP1A2POLBHTTLMNAALDH1A1
SCHEMBL13870082 0.78 ALDH1A1 (0.41) MAPTCYP1A2POLBHTTLMNA
SCHEMBL21243339 0.77 CYP1A2 (0.37) MAPTCYP1A2POLBHPGDHTT
SCHEMBL13870084 0.77 ALDH1A1 (0.36) CYP1A2ALDH1A1MEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947472-B2 Lubricant base oil for power transmission NEW JAPAN CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION NEW JAPAN CHEMICAL CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947472-B2 Lubricant base oil for power transmission DNAH12, DYNC1LI1, DYNC1LI2 MAPT 1563/4885CYP1A2 3601/4885POLB 1080/4885
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION DNAH12, DYNC1LI1, DYNC1LI2 MAPT 1563/4885CYP1A2 3601/4885POLB 1080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.