SCHEMBL21243369

SCHEMBL21243369

CCCCC1CCC(COC(=O)C2CCC(C)CC2C(=O)OCC2CCC(CCCC)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
MAPT P10636 2/20 0.38
CYP1A2 P05177 2/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
GAA P10253 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
NAAA Q02083 1/20 0.34
TP53 P04637 2/20 0.34
CYP3A4 P08684 1/20 0.34
PKM P14618 1/20 0.33
TLR4 O00206 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243382 0.91 TRPM8 (0.36) LMNAMAPTTRPM8TP53CYP3A4
SCHEMBL21243334 0.86 CYP1A2 (0.48) HTTLMNAMAPK1MAPTCYP1A2
SCHEMBL21243329 0.86 TP53 (0.41) LMNATRPM8TP53CYP3A4
SCHEMBL21243358 0.84 TRPM8 (0.38) LMNATRPM8TP53CYP3A4
SCHEMBL21243337 0.81 LIPA (0.39) HTTMAPTGAATRPM8TP53
SCHEMBL21243331 0.80 TP53 (0.46) LMNATRPM8TP53CYP3A4MEN1
SCHEMBL21243363 0.79 MAPT (0.43) HTTLMNAMAPK1MAPTCYP1A2
SCHEMBL1196090 0.78 ALDH1A1 (0.44) LMNAPOLBHPGDTRPM8NAAA
SCHEMBL21243375 0.78 TRPM8 (0.41) LMNATRPM8TP53CYP3A4
SCHEMBL1196205 0.77 PPM1B (0.44) TRPM8TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947472-B2 Lubricant base oil for power transmission NEW JAPAN CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION NEW JAPAN CHEMICAL CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947472-B2 Lubricant base oil for power transmission DNAH12, DYNC1LI1, DYNC1LI2 HTT 2085/4885LMNA 2553/4885MAPK1 1043/4885
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION DNAH12, DYNC1LI1, DYNC1LI2 HTT 2085/4885LMNA 2553/4885MAPK1 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.