SCHEMBL21243832

SCHEMBL21243832

O=C(O)Cc1ccc(Oc2ccc(Oc3ccc(CC(=O)O)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.72
NR3C1 P04150 2/20 0.62
CA2 P00918 1/20 0.60
CAMK2A Q9UQM7 1/20 0.60
AKR1B1 P15121 1/20 0.58
FFAR1 O14842 2/20 0.57
LMNA P02545 2/20 0.56
GAA P10253 2/20 0.56
TSHR P16473 2/20 0.56
PTGS1 P23219 2/20 0.56
ABCC4 O15439 1/20 0.56
HTT P42858 1/20 0.56
KDM4E B2RXH2 2/20 0.54
POLB P06746 2/20 0.54
RGS12 O14924 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
NFKB1 P19838 1/20 0.54
APEX1 P27695 1/20 0.54
THPO P40225 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2999416 1.00 SRD5A2 (0.72) SRD5A2NR3C1CA2CAMK2AAKR1B1
SCHEMBL1145770 0.94 SRD5A2 (0.83) SRD5A2NR3C1AKR1B1FFAR1LMNA
SCHEMBL2353788 0.92 CA2 (0.76) SRD5A2NR3C1CA2CAMK2AAKR1B1
SCHEMBL11562567 0.90 SRD5A2 (0.62) SRD5A2NR3C1CA2CAMK2AAKR1B1
SCHEMBL5924483 0.90 SRD5A2 (0.62) SRD5A2NR3C1CA2CAMK2AAKR1B1
SCHEMBL6441891 0.90 SRD5A2 (0.62) SRD5A2NR3C1CA2CAMK2AFFAR1
SCHEMBL3500048 0.90 SRD5A2 (0.62) SRD5A2NR3C1CA2CAMK2AAKR1B1
SCHEMBL16866564 0.88 SRD5A2 (0.60) SRD5A2NR3C1CA2CAMK2AAKR1B1
SCHEMBL8969156 0.88 SRD5A2 (0.70) SRD5A2NR3C1AKR1B1FFAR1LMNA
SCHEMBL21753830 0.88 SRD5A2 (0.75) SRD5A2NR3C1AKR1B1FFAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
EP-4148047-A1 EPOXY RESIN The Boeing Company (US) 2023-03-15 EP disclosed
US-20210355269-A1 EPOXY RESIN COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2021-11-18 US disclosed
US-11059937-B2 Epoxy resin THE BOEING COMPANY (US) 2021-07-13 US disclosed
US-20190248953-A1 EPOXY RESIN THE BOEING COMPANY 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718707-B2 Epoxy resin EPHX2, EPHX1, CBR1 SRD5A2 1255/4885NR3C1 1767/4885CA2 4706/4885
US-20210355269-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 SRD5A2 1255/4885NR3C1 1767/4885CA2 4706/4885
US-20190248953-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 SRD5A2 1255/4885NR3C1 1767/4885CA2 4706/4885
US-11059937-B2 Epoxy resin EPHX2, EPHX1, CBR1 SRD5A2 1255/4885NR3C1 1767/4885CA2 4706/4885
US-20230312812-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 SRD5A2 1255/4885NR3C1 1767/4885CA2 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.