SCHEMBL8969156

SCHEMBL8969156

O=C(O)Cc1ccc(Oc2cccc(Oc3ccc(CC(=O)O)cc3)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.70
FFAR1 O14842 3/20 0.64
NR3C1 P04150 2/20 0.60
FFAR4 Q5NUL3 1/20 0.52
AKR1B1 P15121 1/20 0.52
ABCC4 O15439 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
LTA4H P09960 1/20 0.50
AKR1C3 P42330 1/20 0.50
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145770 0.90 SRD5A2 (0.83) SRD5A2FFAR1NR3C1FFAR4AKR1B1
SCHEMBL6155118 0.89 SRD5A2 (0.60) SRD5A2FFAR1NR3C1FFAR4AKR1B1
SCHEMBL31657152 0.89 AKR1C3 (0.70) SRD5A2FFAR1NR3C1AKR1C3
SCHEMBL21243832 0.88 SRD5A2 (0.72) SRD5A2FFAR1NR3C1AKR1B1ABCC4
SCHEMBL2999416 0.88 SRD5A2 (0.72) SRD5A2FFAR1NR3C1AKR1B1ABCC4
SCHEMBL21753830 0.85 SRD5A2 (0.75) SRD5A2FFAR1NR3C1AKR1B1ABCC4
SCHEMBL415441 0.85 FFAR1 (0.68) SRD5A2FFAR1NR3C1FFAR4AKR1B1
SCHEMBL6239573 0.85 FFAR1 (0.76) SRD5A2FFAR1NR3C1FFAR4AKR1B1
SCHEMBL11077637 0.85 THRB (0.60) SRD5A2FFAR1NR3C1FFAR4LTA4H
SCHEMBL6235731 0.84 SRD5A2 (0.64) SRD5A2FFAR1NR3C1AKR1B1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699216-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-06 EP disclosed
WO-1994028052-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-08 WO disclosed
US-5288835-A 4,4*-bis(hydroxyphenoxy)biphenyl as one of the monomer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-22 US disclosed