Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.75 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145770 | 0.94 | SRD5A2 (0.83) | SRD5A2ABCC4LMNAGAATSHR | |
| SCHEMBL21243832 | 0.88 | SRD5A2 (0.72) | SRD5A2ABCC4LMNAGAATSHR | |
| SCHEMBL2999416 | 0.88 | SRD5A2 (0.72) | SRD5A2ABCC4LMNAGAATSHR | |
| SCHEMBL8969156 | 0.85 | SRD5A2 (0.70) | SRD5A2ABCC4LMNAGAATSHR | |
| Felbinac SCHEMBL26084 | 0.84 | LMNA (1.00) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL5926621 | 0.82 | FFAR1 (0.90) | SRD5A2FFAR1MMP12MMP13AKR1B1 | |
| Felbinac SCHEMBL8844919 | 0.82 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL384892 | 0.82 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL28284677 | 0.82 | LMNA (0.95) | SRD5A2ABCC4LMNAGAATSHR | |
| Felbinac SCHEMBL28286222 | 0.82 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040326-A1 | PHENYLACETIC ACID DERIVATIVE, AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | 가천대학교 산학협력단 | 2020-02-27 | — | — | WO | disclosed |