Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763259 | 0.87 | LMNA (0.60) | TSHRLCKLMNACYP1A2PTGS1 | |
| SCHEMBL6536372 | 0.87 | CHRNA7 (0.46) | TSHRLCKLMNACYP1A2PTGS1 | |
| SCHEMBL2267205 | 0.85 | TDP1 (0.46) | TSHRLCKLMNACYP1A2PTGS1 | |
| SCHEMBL8751709 | 0.85 | TSHR (0.64) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14378813 | 0.83 | TSHR (0.62) | TSHRLCKALDH1A1KDM4E | |
| SCHEMBL1480744 | 0.83 | LMNA (0.55) | LCKLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL3158759 | 0.81 | TSHR (0.64) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL2516876 | 0.80 | APP (0.58) | TSHRLCKLMNACYP1A2PTGS1 | |
| SCHEMBL197717 | 0.80 | TSHR (0.56) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL18868385 | 0.79 | ALDH1A1 (0.50) | TSHRHIF1AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292859-B2 | Method for producing a polymer by nitroxyl-controlled polymerisation, and polymer | FRAUNHOFER-GESELLSCHAFT ZURFÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2022-04-05 | — | — | US | claimed |
| US-20190248927-A1 | METHOD FOR PRODUCING A POLYMER BY NITROXYL-CONTROLLED POLYMERISATION, AND POLYMER | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2019-08-15 | — | — | US | claimed |
| CN-110100205-B | Method for producing polymers by controlled nitrogen-oxygen polymerization and polymers | 弗劳恩霍夫应用研究促进协会 | 2022-12-30 | — | — | CN | disclosed |
| US-11292859-B2 | Method for producing a polymer by nitroxyl-controlled polymerisation, and polymer | FRAUNHOFER-GESELLSCHAFT ZURFÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2022-04-05 | — | — | US | disclosed |
| US-20190248927-A1 | METHOD FOR PRODUCING A POLYMER BY NITROXYL-CONTROLLED POLYMERISATION, AND POLYMER | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2019-08-15 | — | — | US | disclosed |