SCHEMBL21244263

SCHEMBL21244263

C=CC(=O)OCc1cccc(F)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 1/20 0.40
KMT2A Q03164 1/20 0.40
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39
THRB P10828 2/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
P2RX7 Q99572 1/20 0.36
THRA P10827 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
MAOB P27338 1/20 0.35
F13A1 P00488 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4596466 0.84 ESR1 (0.43) ALDH1A1L3MBTL1THRBKDM4ELMNA
SCHEMBL4606745 0.84 F13A1 (0.46) ALDH1A1NPC1RAB9AL3MBTL1MMP1
SCHEMBL528065 0.84 ALDH1A1 (0.50) ALDH1A1NPC1RAB9AL3MBTL1ATM
SCHEMBL13975601 0.78 CD274 (0.54)
SCHEMBL29577996 0.78 THRB (0.53) ALDH1A1THRBLMNASMN1; SMN2THRA
SCHEMBL10451653 0.78 THRB (0.53) ALDH1A1THRBLMNASMN1; SMN2THRA
SCHEMBL1591973 0.78 MAOB (0.46) ALDH1A1NPC1RAB9AL3MBTL1KMT2A
SCHEMBL27421526 0.77 THRB (0.45) ALDH1A1KMT2ATHRBSMN1; SMN2THRA
SCHEMBL29433901 0.77 MEP1B (0.44) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL28270007 0.76 THRB (0.39) ALDH1A1NPC1RAB9AL3MBTL1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190250510-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) 2019-08-15 US disclosed
US-20190250509-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-15 US disclosed