Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14362399 | 0.78 | ALDH1A1 (0.40) | LMNAALDH1A1TP53HSD17B10TSHR | |
| SCHEMBL862484 | 0.76 | — | — | |
| SCHEMBL19073268 | 0.75 | ALDH1A1 (0.38) | LMNAALDH1A1TP53HSD17B10 | |
| SCHEMBL23264073 | 0.75 | ALDH1A1 (0.38) | LMNAALDH1A1TP53HSD17B10TSHR | |
| SCHEMBL25464043 | 0.75 | ALDH1A1 (0.38) | LMNAALDH1A1TP53HSD17B10 | |
| SCHEMBL23264535 | 0.75 | ALDH1A1 (0.38) | LMNAALDH1A1TP53HSD17B10 | |
| SCHEMBL23830301 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1TP53HSD17B10TSHR | |
| SCHEMBL5064766 | 0.70 | TP53 (0.43) | LMNAALDH1A1TP53HSD17B10TSHR | |
| SCHEMBL23830337 | 0.70 | ALDH1A1 (0.42) | LMNAALDH1A1TP53HSD17B10TSHR | |
| SCHEMBL9602045 | 0.68 | MAPT (0.61) | LMNAALDH1A1CYP1A2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154962-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2019-08-07 | — | — | EP | disclosed |