Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830301 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL21246623 | 0.70 | LMNA (0.48) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL3393888 | 0.68 | HSP90AA1 (0.42) | — | |
| SCHEMBL24924192 | 0.67 | TP53 (0.36) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL3951225 | 0.67 | TP53 (0.36) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL8573829 | 0.67 | TP53 (0.36) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL21794553 | 0.64 | GAA (0.33) | ALDH1A1HPGD | |
| SCHEMBL12261900 | 0.64 | LMNA (0.43) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL5064766 | 0.62 | TP53 (0.43) | ALDH1A1LMNATP53HSD17B10CYP1A2 | |
| SCHEMBL23264073 | 0.62 | ALDH1A1 (0.38) | ALDH1A1LMNATP53HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | CADILA HEALTHCARE LIMITED (IN) | 2021-09-23 | — | — | US | disclosed |
| CN-112543757-A | Condensed azaheteroaryl compounds having antibacterial activity against tubercle bacillus | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | DPEP1, SAT1, PEPD | ALDH1A1 152/4885LMNA 2123/4885TP53 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.